Can mice come through floor vents?
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Mice are incredibly nimble creatures and can squeeze through very small openings. If the floor vents have openings large enough for a mouse to fit through, it's possible for them to enter through those vents. Blocking off or covering vents with mesh or grates designed to keep rodents out can be a good preventive measure. Regularly checking and maintaining the vents can help prevent unwanted critters from entering your home.